Class 12 NEET Chemistry Coordination Compounds

Cis isomer of [Pt(NH3)2‌Cl2] is used as an anticancer drug for treating several types of malignant tumours. When it is injected into the blood stream, the more reactive Cl groups are lost. So the Pt atom bonds to a Natom in guanosine (a part of DNA). This molecule can bond to two different guanosine units and by bridging between them it upsets the normal reproduction of DNA.