Angiotensin-converting enzyme 2 is an enzyme attached to the membrane of cells in the intestines, kidney, testis, gallbladder, and heart.
The angiotensin-converting enzyme-2 (ACE-2) has been identified as the receptor for the SARS-CoV-2 viral angiotensin-converting enzyme 2 (ACE2) acts as an entry point for coronavirus into the Human Body.
ACE2 is discussed in the context of the spread of viral disease. Hence, Option 4 is correct.
ACE2 is a protein on the surface of many cell types.
It is an enzyme that generates small proteins– by cutting up the larger protein angiotensinogen that then goes on to regulate functions in the cell.
Using the spike-like protein on its surface, the SARS-CoV-2 virus binds to ACE2– like a key being inserted into a lock– before entry and infection of cells. Hence, ACE2 acts as a cellular doorway – a receptor– for the virus that causes COVID-19.