UPSC Civil Services 2019 Prelims General Studies Paper I

Overuse and misuse of antimicrobial agents is the single most important cause of development of resistance. They are also used indiscriminately as growth promoters in animals or used to prevent diseases in healthy animals. The antibiotics used in livestock are ingested by humans when they consume food.The transfer of resistant bacteria to humans by farm animals was first noted more than 35 years ago. (says American medical journal). So, #2 & #3 are right this eliminates A and C. Because they don't contain 2or 3.
- According to the 4th World Health Organization (WHO) report on anti-tuberculosis drug resistance: multi-drug resistant tuberculosis (MDR TB) has been shown to be almost twice as common in tuberculosis (TB) patients living with HIV compared to TB patients without HIV. So #4 does seem to have some validity.
Accordingly, the answer should be D.