• The African sleeping sickness is a disease that is caused by protozoans belonging to the genus Trypanosoma. • The infection is spread by the tsetse fly which is endemic to the African continent. • The disease causes fever, swollen lymph glands, aching joints and muscles and in the advanced stages, affects the central nervous system which can be life-threatening. • Entamoeba histolyticais a protozoan which causes amebiasis. • Protozoans Plasmodium vivax causes malaria whereas Leishmania donovani causes Leishmaniasis.