TS EAMCET Medical 8 May 2019 Shift 1 Paper

With respect to DNA synthesis, identify the correct combination of statements.
I. Always the direction of DNA polymerisation is 5' → 3' when referring to the polarity of strand being synthesized.
II. DNA ligase forms hydrogen bonds between two newly synthesized DNA strands.
III. DNA polymerases on their- own cannot initiate the process of replication.
IV. DNA polymerase can catalyse polymerization in both 5' → 3' and 3’ → 5' direction.