Class 12 NEET Biology Principles of Inheritance and Variation Questions Part 2

Autoradiography allows the detection/localisation of radioactive isotope within a biological sample.
Probe is a radiolabelled ss DNA or ss RNA depending on the technique. To identify the mutated gene probe is allowed to hybridise to its complementary DNA in a clone of cells followed by detection using autoradiography. The mutated gene will not appear on the photographic film, because the probe does not have complementarity with the mutated gene.