Class 11 NEET Biology Neural Control and Coordination

(b) Alzheimer disease in humans is associated with the deficiency of acetylcholine. Acetylcholine is the neurotransmitter produced by neurons referred to as cholinergic neurons. Acetylcholine plays a role in skeletal muscle movement, as well as in the regulation of smooth muscle and cardiac muscle. Acetylcholine is synthesised from choline and acetyl coenzyme-A through the action of the enzyme choline acetyl transferase and becomes packaged into membrane-bound vesicles.