Class 12 NEET Biology Biotechnology and Its Applications

(b) RNAi (RNA interference) is triggered by double stranded RNA in a wide variety of organisms including animals, plants and fungi. It involves silencing of a specific mRNA and therefore the expression of a gene by formation of a dsRNA molecule. The dsRNA is formed by binding of a complementary RNA (anti-sense RNA) molecule to original mRNA thereby preventing translation of the original mRNA.