Graduate Pharmacy Aptitude Test (GPAT) 2015 Solved Paper
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Question : 60 of 125
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Characteristics of drug-protein binding
(P) Often parallels drug lipid solubility
(Q) Drug-plasma albumin binding tends to be relatively nonselective
(R) Acidic drugs bind to albumin while basic drug bind to glycoproteins
(S) In rheumatoid arthritis patients, increased alpha1- acidic glycoprotein tends to promote increased lidocaine protein binding
(P) Often parallels drug lipid solubility
(Q) Drug-plasma albumin binding tends to be relatively nonselective
(R) Acidic drugs bind to albumin while basic drug bind to glycoproteins
(S) In rheumatoid arthritis patients, increased alpha1- acidic glycoprotein tends to promote increased lidocaine protein binding
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