Graduate Pharmacy Aptitude Test (GPAT) 2012 Solved Paper

Read the following statements about lyophilization:
[P] : Lyophilization cannot be done in final containers like multiple dose containers.
[Q]: Lyophilized product needs special methods for reconstitution.
[R]: Lyophilization causes protein denaturation in tissues.
[S] : Lyophilization is suitable for drying the thermolabile products.
Choose the correct combination of statements.