GROUP I Transdermal drug delivery system GROUP II Method of penetration (Q) Diffusion controlled system 1. Drug is homogenously dispersed in polymer and then moulded into a patch (Q) Diffusion controlled system 2. Drug reservoir is encapsulated in rate controlling polymer patch (R) Matrix dispersion system 3. Drug is dispersed in hydrophilic polymer and then cross with lipophilic polymer by high shear mechanical force linked (S) Microreservoir system 4. Drug is directly dispersed in polymer patch

Correct Answer is : P-2, Q-4, R-1, S-3

Graduate Pharmacy Aptitude Test (GPAT) 2009 Solved Paper

Question : 44 of 60

Marks: +1, -0

GROUP I Transdermal drug delivery system	GROUP II Method of penetration
(Q) Diffusion controlled system	1. Drug is homogenously dispersed in polymer and then moulded into a patch
(Q) Diffusion controlled system	2. Drug reservoir is encapsulated in rate controlling polymer patch
(R) Matrix dispersion system	3. Drug is dispersed in hydrophilic polymer and then cross with lipophilic polymer by high shear mechanical force linked
(S) Microreservoir system	4. Drug is directly dispersed in polymer patch

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