GROUP I Drug GROUP II Mechanism of action is by inhibition of (P) Levofloxacin 1. DNA dependent RNA polymerase (Q) Caspofungin 2. Topoisomerase II (DNA gyrase) the enzyme that Produces a negative supercoil (R) Aztreonam 3. The synthesis of b(1-2) glycan (S) Rifabutin 4. Cell wall synthesis preferentially binding to a Specific penicillin binding protein

Correct Answer is : P-4,Q-1,R-2,S-3

Graduate Pharmacy Aptitude Test (GPAT) 2009 Solved Paper

Question : 38 of 60

Marks: +1, -0

GROUP I Drug	GROUP II Mechanism of action is by inhibition of
(P) Levofloxacin	1. DNA dependent RNA polymerase
(Q) Caspofungin	2. Topoisomerase II (DNA gyrase) the enzyme that Produces a negative supercoil
(R) Aztreonam	3. The synthesis of b(1−2) glycan
(S) Rifabutin	4. Cell wall synthesis preferentially binding to a Specific penicillin binding protein

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