Derivatives of cortisol and their structural modification are GROUP I Derivative GROUP II Structural modifaction (P) Prednisolone (1) 1, 2-dehydro, 9 \alpha-fluoro, 16 \alpha-methyl (Q) Dexamethasone (2) 1, 2-dehydro (R) Betamethasone (3) 1, 2-dehydro, 9 \alpha-fluoro, 16 \beta-methyl (S) Triamcinolone (4) 1,2 -dehydro, 9 \alpha-fluoro, 16 \alpha-hydroxy

Correct Answer is : P-1, Q-3, R-4,S-2

Graduate Pharmacy Aptitude Test (GPAT) 2008 Solved Paper

Question : 58 of 85

Marks: +1, -0

Derivatives of cortisol and their structural modification are

GROUP I Derivative	GROUP II Structural modifaction
(P) Prednisolone	(1) 1, 2-dehydro, 9α-fluoro, 16α-methyl
(Q) Dexamethasone	(2) 1, 2-dehydro
(R) Betamethasone	(3) 1, 2-dehydro, 9α-fluoro, 16β-methyl
(S) Triamcinolone	(4) 1,2 -dehydro, 9α-fluoro, 16α-hydroxy

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