GROUP I Method of purification GROUP II Effect on water quality (P) Entrainment preventive distillation (1) CFU value and endotoxin content usually increases (Q) Simple distillation (2) Pyrogen free water (R) Reverse osmosis (3) Endotoxins and pyrogens are not removed (S) Ion-exchange (4) Small organic molecules (molwt, approx. less than 200) are not removed

Correct Answer is : P-2, Q-3, R-4, S-1

Graduate Pharmacy Aptitude Test (GPAT) 2007 Solved Paper

Question : 62 of 85

Marks: +1, -0

GROUP I Method of purification	GROUP II Effect on water quality
(P) Entrainment preventive distillation	(1) CFU value and endotoxin content usually increases
(Q) Simple distillation	(2) Pyrogen free water
(R) Reverse osmosis	(3) Endotoxins and pyrogens are not removed
(S) Ion-exchange	(4) Small organic molecules (molwt, approx. less than 200) are not removed

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