GROUP I Film defects GROUP II Explanation (P) Orange peel effect (1) Inadequate spreading of the coating solution before Drying causes a bumping effect on the coating (Q) Blistering (2) It is the result of drying coated tablets in ovens, due to too Rapid evaporation of the solvent from the core and the Effect of high temperature on the film (R) Cracking (3) Occurs due to processing temperature used is too high for Aparticular formulation (S) Bloom (4) Occurs if internal stress in the film exceed the tensile Strength of the film

Correct Answer is : P−1,Q−2,R−4,S−3

Graduate Pharmacy Aptitude Test (GPAT) 2006 Solved Paper

Question : 61 of 85

Marks: +1, -0

GROUP I Film defects	GROUP II Explanation
(P) Orange peel effect	(1) Inadequate spreading of the coating solution before Drying causes a bumping effect on the coating
(Q) Blistering	(2) It is the result of drying coated tablets in ovens, due to too Rapid evaporation of the solvent from the core and the Effect of high temperature on the film
(R) Cracking	(3) Occurs due to processing temperature used is too high for Aparticular formulation
(S) Bloom	(4) Occurs if internal stress in the film exceed the tensile Strength of the film

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