Graduate Pharmacy Aptitude Test (GPAT) 2006 Solved Paper

Question : 35 of 85

Marks: +1, -0

Diagnostic strips such as Diastrix/Clinistix, used commonly to monitor diabetes, work of which of the following principles:-

The strips are coated with glucose oxidase, peroxidase and o-toluidine. Any glucose in the test Solution when exposed to the strips, gets oxidixed leading to the release of hydrogen peroxide, the atter in turnoxidises to o-toluidine to yield a blue colour
The strips are coated with phenolphthalein analogue, which when exposed to acidic glucose solution, yield a blue colour
The strips are coated with glucose epimerase and thymol blue, which when exposed to glucose, epimerize resulting in blue colour
The strips are coated with leucine synthase and ninhydrin. Glucose, if any in the test solution gets converted into amino acids, which in turn react with ninhydrin to yield its blue colour.

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