COMEDK 2024 Shift 1 Paper

To determine which of the statements about Insulin are correct, let's examine each statement individually:
[A] Insulin is a globular protein consisting of 51 Amino acids.
This statement is correct. Insulin is indeed a globular protein, and the most common form of human insulin consists of 51 amino acids.
[B] Insulin is constituted of 3 polypeptide chains linked together.
This statement is incorrect. Insulin is made up of 2 polypeptide chains, not 3 . The correct number of polypeptide chains in insulin is two.
[C] Insulin is constituted of 2 polypeptide chains linked together by disulphide bonds.
This statement is correct. Insulin has two polypeptide chains, the A-chain and the B-chain, which are linked together by disulphide bonds.
[D] The 3 polypeptide chains in Insulin are linked together by Hydrogen bonding.
This statement is incorrect for two reasons. First, insulin does not have 3 polypeptide chains, and second, the chains are linked by disulphide bonds, not hydrogen bonds.
From this analysis, we can see that the correct statements are [A] and [C]. Therefore, the correct option is:
Option B
[A] & [C]